Glucose Transporters

PYQ 1 [AIIMS PG 2018] The mechanism by which glucose is absorbed in the intestine is:
A. Primary active transport 
B. Secondary active transport 
C. Facilitated diffusion 
D. Any of the above 
Answer: B
Types of glucose transporters: 
There are various types of glucose transporters, also known as GLUT proteins. 
✓GLUT1: Found in many tissues, including red blood cells and the blood-brain barrier. It ensures a constant glucose supply. Example: Erythrocytes (red blood cells). 
✓GLUT2: Predominantly in the liver, pancreas, and small intestine. It plays a role in glucose sensing. Example: Liver cells. 
✓GLUT3: Mainly in neurons, ensuring a continuous glucose supply to the brain. Example: Neurons in the central nervous system. 
✓GLUT4: Present in muscle and adipose (fat) tissues, facilitating insulin-dependent glucose uptake. Example: Skeletal muscle cells.
 ✓GLUT5: Primarily found in the small intestine and is responsible for fructose transport. Example: Small intestinal cells.

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